Combine turkey, stuffing mix, milk, Parmesan, onion, pepper, egg, salt, garlic powder, and pepper in a large bowl and mix well with your hands.
Place two slices of bread on the bottom of a baking sheet. Spoon mixture onto the bread and shape it into a loaf.
Bake for 30 minutes and remove from the oven for the sauce.
In a small bowl, stir together the ketchup, sugar, mustard, and Worcestershire sauce. Spoon over the meatloaf and return to the oven for 30 minutes or until loaf is cooked through.
Let sit 5 minutes before slicing and serving. Remove the bread from the bottom of each slice of meatloaf before serving.
Stove Top Stuffing adds a lot of flavor to the meatloaf as well as keeps it moist. If you substitute it with something else, you'll want to adjust the seasoning accordingly and realize that the meatloaf may not be as moist.The bread is not necessary, but's an easy way to soak up the liquid that will release from the meatloaf. It's simple to remove or just leave it on and serve it - not a lot of fat comes out of turkey meatloaf and the bread is flavorful.This turkey meatloaf should reach an internal temperature of 165 degrees before serving.