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Cajun chicken Alfredo in skillet.
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Cajun Chicken Alfredo

Rich and creamy Alfredo sauce is a breeze to make. We've spiced it up with juicy chicken and Cajun flavors for a quick weeknight meal that our entire family loves.
Course Main Course
Cuisine Cajun
Prep Time 10 minutes
Cook Time 30 minutes
Total Time 40 minutes
Servings 6 servings
Calories 878kcal

Ingredients

  • 1 pound boneless, skinless chicken breasts
  • 2 teaspoons Cajun seasoning plus more, to taste
  • 1 tablespoon olive oil
  • 16 ounces fettucine
  • 1/2 cup butter
  • 2 cloves garlic minced
  • 1 cup heavy cream
  • 8 ounces shredded Parmesan
  • 4 ounces shredded mozzarella

Instructions

  • Pound the chicken breasts to an even thickness. Season with the Cajun seasoning, making sure to coat both sides of the chicken.
  • Bring a large pot of salted water to a boil.
  • Heat a large oven proof skillet over medium heat. Swirl in the oil to coat the pan.
  • Add the chicken to the skillet and cook through, flipping halfway through cooking, about 10 minutes.
  • Remove the chicken from the skillet and place on a cutting board to rest.
  • Add the fettucine to the boiling water and cook until al dente.
  • While the pasta is boiling, place the skillet back over medium heat and add the butter. Once melted, stir in the garlic and cook for about 30 seconds.
  • Add the heavy cream to the skillet and cook for 2-3 minutes to heat the cream. Once hot, add the cheeses and whisk together until the sauce is smooth and combined.
  • Taste and season with Cajun seasoning, as desired.
  • Drain the pasta and add it to the sauce. Toss to coat.
  • Slice or chop the chicken and serve with the pasta.

Video

Notes

Some Cajun seasoning blends are very salty. Taste as you go and season to taste.

Nutrition

Calories: 878kcal | Carbohydrates: 57g | Protein: 46g | Fat: 52g | Saturated Fat: 29g | Polyunsaturated Fat: 3g | Monounsaturated Fat: 16g | Trans Fat: 1g | Cholesterol: 248mg | Sodium: 978mg | Potassium: 567mg | Fiber: 3g | Sugar: 2g | Vitamin A: 1877IU | Vitamin C: 1mg | Calcium: 607mg | Iron: 2mg