5 from 2 votes

Cajun Chicken Alfredo

Prep Time
10 mins
Cook Time
30 mins
Total Time
40 mins
Servings: 8 servings
Course: Main Course
Cuisine: Cajun
Keyword: easy pasta recipes, easy recipes, weeknight dinner recipes
Calories: 694 kcal

This chicken Alfredo is creamy dreamy perfection! It's spiced up with some Cajun flavors!


  • 1 pound boneless skinless chicken breasts
  • Cajun Seasoning enough to coat the chicken
  • 16 ounces fettucini
  • 2 tablespoon olive oil
  • 2 cloves garlic minced
  • 1 cup heavy cream
  • 1/2 cup butter 1 stick
  • 8 ounces Parmesan cheese grated
  • 4 ounces Pecorino Romano cheese grated
  • Salt and pepper to taste


  1. Pound the chicken breasts to an even thickness. Coat the chicken in the Cajun seasoning.
  2. Heat a large oven proof skillet over medium heat and preheat the oven to 350 degrees.
  3. Bring a large pot of water to a boil.
  4. Pour 1 tablespoon of the olive oil into the skillet. Add the chicken breasts and ook for 5 minutes.
  5. Flip the chicken breasts over and cook for 3 more minutes.
  6. Place the skillet in the oven and allow to cook through, about 5 more minutes.
  7. Remove the skillet from the oven and place the chicken on a cutting board to rest.
  8. Add the fettucini to the boiling water and cook until al dente.
  9. While the pasta is boiling, place the skillet back over medium heat and add the remaining tablespoon of olive oil. Stir in the garlic and cook for 1 minute. (You could add in some sun-dried tomatoes here, but my husband would divorce me if I did such a thing.)
  10. Add the heavy cream and butter to the skillet and cook until the butter has melted and it's heated through, stirring often.
  11. While the butter is melting, slice the chicken into bite sized pieces.
  12. Add the cheese to the cream mixture and stir until fully melted and combined.
  13. Drain the pasta and add it to the alfredo sauce. Add in the chicken and toss to coat.
  14. Salt and pepper, to taste.
Nutrition Facts
Cajun Chicken Alfredo
Amount Per Serving
Calories 694 Calories from Fat 369
% Daily Value*
Fat 41g63%
Saturated Fat 23g144%
Cholesterol 188mg63%
Sodium 776mg34%
Potassium 410mg12%
Carbohydrates 42g14%
Fiber 1g4%
Sugar 1g1%
Protein 36g72%
Vitamin A 1105IU22%
Vitamin C 0.4mg0%
Calcium 533mg53%
Iron 1.7mg9%
* Percent Daily Values are based on a 2000 calorie diet.

Nutrition Disclaimer: All information presented on this site is intended for informational purposes only. I am not a certified nutritionist and any nutritional information shared on should only be used as a general guideline.