baked manicotti stuffed with cheese and spinach

Four Cheese Spinach Manicotti

Prep Time
20 mins
Cook Time
50 mins
Total Time
1 hr 10 mins
Servings: 6
Course: Main Course
Cuisine: Italian
Keyword: family recipes, pasta
Calories: 659 kcal

Extra cheesy pasta is always a win in our house!


For the manicotti:
  • 12 ounces manicotti
  • 16 ounces Ricotta cheese
  • 6 ounces Mozzarella cheese shredded
  • 6 ounces Parmesan shredded
  • 4 ounces cream cheese
  • 1/2 teaspoon Italian seasoning
  • 1/2 teaspoon dried basil
  • 1 tablespoon olive oil
  • 1 cup finely chopped fresh baby Spinach
  • 2 tablespoons minced onion
  • 1 clove garlic minced
  • 2 cups marinara sauce
  • 1 tablespoon fresh parsley minced
Basic Marinara Sauce:
  • 1 tablespoon olive oil
  • 1/2 medium onion minced
  • 3 cloves garlic minced
  • 1 teaspoon Red pepper flakes
  • 45 ounces crushed tomatoes
  • 2 tablespoons tomato paste
  • 2 tablespoons chopped basil
  • 2 tablespoons chopped oregano
  • 1 teaspoon salt
  • 1/4 teaspoon sugar


For the manicotti:
  1. Bring a large pot of salted water to a boil. Add in the manicotti and cook for 7 minutes. Drain.
  2. Set aside the pasta to cool and begin making the filling. 

  3. In a large bowl, mix together the Ricotta cheese, 3 ounces of Mozzarella, 3 ounces of Parmesan, cream cheese, Italian seasoning, and basil.

  4. Heat the olive oil in a small skillet over medium heat. Add the spinach, onion, and garlic and cook until the onion is translucent and the spinach has wilted, about 5 minutes.

  5. Add the spinach to the cheese mixture and stir well to combine.

  6. When the pasta is cool enough to handle, use a small spoon to scoop the filling into the pasta. Alternately, place the filling in a plastic bag and snip off the end. Squirt the filling into the manicotti.

  7. Cover the bottom of a 9x13 baking dish with a thin layer of marinara sauce. Arrange your pasta in the baking dish. Cover with the remaining marinara sauce and top with the remaining cheese. 

  8. Bake in a preheated 350 degree oven for about 20 minutes or until the cheese is melted and starting to browned on top. Sprinkle with parsley before serving.

For the sauce:
  1. Heat the oil in a large sauce pan over medium heat. Add the onion and garlic and saute until soft and fragrant, about 5 minutes. 

  2. Add the remaining ingredients, stir to combine, and simmer for 30 minutes over low heat, stirring occasionally.

  3. Store sauce tightly covered in the refrigerator for up to 5 days. 

Recipe Notes

Use store bought marinara, if preferred.

Nutrition Facts
Four Cheese Spinach Manicotti
Amount Per Serving (1 g)
Calories 659 Calories from Fat 288
% Daily Value*
Fat 32g49%
Saturated Fat 18g113%
Cholesterol 97mg32%
Sodium 1085mg47%
Potassium 591mg17%
Carbohydrates 55g18%
Fiber 3g13%
Sugar 6g7%
Protein 36g72%
Vitamin A 1705IU34%
Vitamin C 7.8mg9%
Calcium 726mg73%
Iron 2.7mg15%
* Percent Daily Values are based on a 2000 calorie diet.

Nutrition Disclaimer: All information presented on this site is intended for informational purposes only. I am not a certified nutritionist and any nutritional information shared on should only be used as a general guideline.